Fig. 4: DNA methylation-based classification of PD.

a Density distribution of the SGPD-derived DNA methylation-based classifier in the PEG cohort. Orange and gray represent the distributions of the z-scaled classifier in PD cases and controls in the PEG cohort (respectively). b Area under the receiver operator characteristic curve (AUC) of the SGPD-based DNA methylation classifier in the PEG cohort (AUC = 0.70, 95% CI = 0.66–0.75).