Fig. 3: DAP is not an NMD inhibitor and is not toxic.
From: 2,6-Diaminopurine as a highly potent corrector of UGA nonsense mutations
a Ratio of the level of p53 mRNA to that of GAPDH mRNA, as measured by RT-PCR, in Calu-6 cells treated with DMSO, DAP, or G418. b Adenylate kinase activity in the culture medium of HeLa cells treated with DMSO (0), increasing amounts of DAP, or the apoptosis inducer staurosporine (STS). The results presented in this figure are representative of two independent experiments. p-values (p) were calculated using Student’s t-test. Source data are provided as a Source Data file.
