Table 1 Transcription factors, cofactors, and chromatin remodeling proteins with allelic patterns that are correlated with Ifng expression in Th1.

From: Transcription factor p73 regulates Th1 differentiation

Gene category

Genes (P < 0.001)

Transcription factors (n = 32)

Dlx2, Ebf1, Esr1, Etv2, Foxd3, Foxj2, Foxm1, Foxo3, Glis3, Hif1a, Irf4, Junb, Mef2c, Myt1l, Npas2, Npas3, Nr3c2, Nr6a1, Olig3, Pbx1, Roraa, Runx2, Runx3, Satb2, Stat1a, Stat4, Tcf12, Tcf4, Trp73a, Uncx, Vdr, Zbtb17

Transcription cofactors (n = 12)

Csrp1, Dcc, Greb1, Ifi203, Lmcd1, Mybbp1a, Pdlim1, Rbbp9, Rbpms, Sap130, Spen, Yaf2

Chromatin remodeling proteins (n = 5)

Cbx7, Hdac1, Hdac9, Itgb3bp, Jmjd1c

  1. Genes were identified by haplotype-based computational genetic mapping, with the pattern of genetic variation significantly correlated with Ifng mRNA in Th1 (P < 0.001). Genes from category transcription factors, transcription cofactors and chromatin remodeling proteins are shown in this table. P values were calculated using analysis of variance (ANOVA)-based statistical modeling. Exact P values for each gene are listed in Supplementary Table 1.
  2. aGenes with allelic patterns that were correlated with Ifng expression at three time points.
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