Fig. 7: MC-derived EC develop endothelial function.
From: Endothelialization of arterial vascular grafts by circulating monocytes
a MCEC differentiated on FN or iVEGF uptake acetylated LDL. MC on day 0 are unable to uptake LDL compared to traditionally activated, LPS stimulated MΦ, MCEC on FN or VEGF or HUVEC or HCAEC. (****p < 0.0001) statistical significance using one-way ANOVA and Sidak’s test (DF = 12, F = 205.1); n = 3 independent biological replicates; error bars indicate ±SD of the mean. MCEC differentiated on FN (b) or VEGF (c) formed tubular networks when cultured on Matrigel. Representative immunostaining for the monocyte markers CD16 (pink), endothelial marker CD144 (green), and CD31 (red) over n = 5 independent biological replicates.
