Table 1 Baseline characteristics of participants in the discovery and replication cohorts.
Cohort | Ancestry | No. of cases | No. of controls | Total | Genotyping platform | Imputation reference population panel |
|---|---|---|---|---|---|---|
Asian Cohorts | ||||||
Chinese Discovery | East Asian | 561 | 904 | 1465 | Zhonghua-8 chip (Illumina) | 1000G Phase 3 East Asians |
Korean Discovery | East Asian | 164 | 708 | 872 | MEGA chip (Illumina) | 1000G Phase 3 East Asians |
Japanese Discovery | East Asian | 81 | 358 | 439 | MEGA chip (Illumina) | 1000G Phase 3 East Asians |
Chinese Replication | East Asian | 826 | 1239 | 2065 | KASP (targeted) | – |
All Asian | 1632 | 3209 | 4841 | |||
European Cohorts | ||||||
European Discovery 1 | European | 611 | 1246 | 1857 | MEGA chip (Illumina) | 1000G Phase 3 Europeans |
European Discovery 2 | European | 1045 | 1094 | 2139 | MEGA chip (Illumina) | 1000G Phase 3 Europeans |
Turkish Discovery | European | 254 | 336 | 590 | MEGA chip (Illumina) | 1000G Phase 3 Europeans |
Sardinian Discovery | European | 93 | 1498 | 1591 | OmniExpress (Illumina) | 1000G Phase 3 Europeans |
GCKD Discovery | European | 147 | 1655a | 1802 | Omni2.5Exome (Illumina) | HRC 1.1 |
All European | 2150 | 5829 | 7979 | |||
All Participants | 3782 | 9038 | 12,820 | |||
