Fig. 5: Gene expression analysis of TnikWT and Tnik−/− memory p14 T cells.
From: TNIK signaling imprints CD8+ T cell memory formation early after priming
a GO enrichment analysis of the biological pathways significantly affected in D80 KO vs WT p14 T cells. b GSEA for glucose metabolism. c Gene network and canonical pathway analysis highlighting the regulation and interrelation of metabolic assigned processes. d, e Heatmap of differentially expressed genes assigned to specific clusters in KO vs WT memory p14 T cells. Highlighted genes in the clustered heatmaps are discussed. NES Normalized Enrichment Score. Also see Supplementary Fig. 5 and Supplementary Data 2. Source data are provided as a Source Data file.
