Fig. 2: Available melanoma models.
a A large number of in vitro models are available to investigate specific properties of melanoma cells, including proliferation, migration, invasion, metastasis, heterogeneity, plasticity, and microenvironment interactions. b In vivo models capable of investigating adaptive immune dynamics require murine melanoma models, whereas (c) models utilizing human melanoma tumor models lack functional adaptive human systems. Scientific illustration toolkits from Motifolio (www.motifolio.com) were used to generate this figure.
