Table 1 Lynch syndrome patient information and tumor characteristics.

From: Limiting oxidative DNA damage reduces microbe-induced colitis-associated colorectal cancer

Patient

Gene

Mutation

Cancer stage

Cancer site

Age at diagnosis

Gender

Other cancera

1

MSH2

Frameshift

T3, N0, M0

Hepatic flexure

36.8

Female

Endometrial cancer @40.5

2

PMS2

Missense

T4a, N0, M0

Transverse

54.0

Male

Prostate cancer @60.4

3

PMS2

Frameshift

T4b, N0, M0

Rectum

29.2

Male

Testis cancer @36.4

4

PMS2

Frameshift

T3, N0, M0

Sigmoid

64.9

Male

Hepatic flexure cancer @71.2

5

MSH2

Deletion

T4, N0, M1

Cecum

60

Female

Endometrium @33

6

MSH2

Deletion

T4, N2, M0

Rectum

43

Female

Transverse colon @40

7

PMS2

Frameshift

T3, N0, M0

Sigmoid

64

Male

None

  1. aOther cancer reported for patient and the age of diagnosis.