Table 1 Lynch syndrome patient information and tumor characteristics.
From: Limiting oxidative DNA damage reduces microbe-induced colitis-associated colorectal cancer
Patient | Gene | Mutation | Cancer stage | Cancer site | Age at diagnosis | Gender | Other cancera |
---|---|---|---|---|---|---|---|
1 | MSH2 | Frameshift | T3, N0, M0 | Hepatic flexure | 36.8 | Female | Endometrial cancer @40.5 |
2 | PMS2 | Missense | T4a, N0, M0 | Transverse | 54.0 | Male | Prostate cancer @60.4 |
3 | PMS2 | Frameshift | T4b, N0, M0 | Rectum | 29.2 | Male | Testis cancer @36.4 |
4 | PMS2 | Frameshift | T3, N0, M0 | Sigmoid | 64.9 | Male | Hepatic flexure cancer @71.2 |
5 | MSH2 | Deletion | T4, N0, M1 | Cecum | 60 | Female | Endometrium @33 |
6 | MSH2 | Deletion | T4, N2, M0 | Rectum | 43 | Female | Transverse colon @40 |
7 | PMS2 | Frameshift | T3, N0, M0 | Sigmoid | 64 | Male | None |