Fig. 4: Differential dynamic of chromatin structure reorganization between normal and SCNT embryos.
From: Chromatin architecture reorganization in murine somatic cell nuclear transfer embryos
a Heatmaps showing the intrachromosomal interaction probabilities relative to genomic distance that are normalized by the P(s) ~ s−1 values. Dashed boxes indicate the developmental stages and genomic distance with differential interaction probabilities between SCNT and fertilization-derived embryos. Source data are provided as a Source Data file. b Ratios of interaction frequencies between compartments A & B to those between compartments A & A or B & B (n = 323). Boxes show 25th, 50th and 75th percentiles and whiskers show 1.5× the inter-quartile range. The p values were calculated by a two-sided Wilcoxon rank-sum test with BH multiple testing correction Source data and exact p-value are provided as a Source Data file. c RTI across all stages (n = 2057). Boxes show 25th, 50th and 75th percentiles and whiskers show 1.5× the inter-quartile range. The two-sided p values were calculated by the Kruskal–Wallis test with Dunn’s multiple comparison test and adjusted by default with the holm method (N.S., not significant). Source data and exact p-value are provided as a Source Data file.
