Fig. 3: Crystal structures of TbGMPR C318A with or without GMP. | Nature Communications

Fig. 3: Crystal structures of TbGMPR C318A with or without GMP.

From: Allosteric regulation accompanied by oligomeric state changes of Trypanosoma brucei GMP reductase through cystathionine-β-synthase domain

Fig. 3

Cartoon representation of the octameric structures of C318A apo (relaxed form, a) and C318A/GMP (twisted form, b), each of which are composed of two tetramers. Tetramer 1 (subunits A–D) and tetramer 2 (subunits A′–D′) are colored in light and dark blue, respectively. GMP molecules are shown as yellow stick representations. Note that C318A/GMP (b; right panel) is compressed compared to C318A apo (a; right panel).

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