Table 3 Analysis of oligomeric state of TbGMPR WT and TbGMPR∆CBS.

From: Allosteric regulation accompanied by oligomeric state changes of Trypanosoma brucei GMP reductase through cystathionine-β-synthase domain

TbGMPR

Ligand

Mass (kDa)

Tetramer (%)

Octamer, relaxed (%)

Octamer, twisted (%)

WT

None

494

0

53.2

46.8

WT

GMP

453

2.2

0

97.8

WT

GTP

462

0

0

100

WT

ATP

314

60.8

28.0

11.2

∆CBS

None

137

—

—

—

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