Fig. 4: Correlation between individual cytokine responses and time since diagnosis.
From: α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson’s disease
Cohorts 1 and 2 combined (n = 96 PD patients). The Y-axis shows the magnitude of responses a IFNγ, b IL-5, and c IL-10, against the α-syn peptide pool as SFC per 106 cultured PBMC. The X-axis shows the years since PD diagnosis. Each point represents one donor. Because many participants showed no response, there are overlapping points at the limit of detection (100 SFC). The number of patients in each quadrant is indicated in each graph. Two-tailed Fisher’s exact test.
