Table 1 Subject characteristics of control and NAFL participants, patients with T2D and GSD1a.

Age (years)

59 ± 6.8

58 ± 7.1

65 ± 4.5

37 ± 12.3^a–c

BMI (kg/m²)

29.1 ± 2.3

30.7 ± 3.1

29.4 ± 4.2

27.5 ± 3.2

Sex (f/m)

6/1

7/8

2/7

5/2

Body fat (%)

42.1 ± 8.1

42.1 ± 7.8

34.1 ± 5.8

–

Plasma glucose (mmol/L)

5.2 ± 0.4

5.6 ± 0.5

7.5 ± 1.1^{a, b}

3.9 ± 0.8^a–c

Plasma insulin (pmol/L)

35.2 ± 8.1

89.8 ± 40.4^a

72.8 ± 58.3

13.8 ± 5.0^{b, c}

Plasma NEFA (mmol/L)

667 ± 58

623 ± 141

566 ± 211

876 ± 421

Plasma TG (mmol/L)

1.5 ± 0.8

2.6 ± 1.2

1.6 ± 0.5

5.0 ± 1.5^a–c

ALT (U/L)

22 ± 4.1

35 ± 14.4

27 ± 11.4

18 ± 4.9^b

AST (U/L)

22 ± 3.7

28 ± 6.3

23 ± 5.9

34 ± 9.3 ^{a, c}

Intrahepatic fat content (% weight/weight)

2.2 ± 1.3

14.4 ± 10.4^a

6.9 ± 5.2

16.5 ± 18.9^a