Fig. 2: Detection of sSR-A in a large-scale, multicenter study. | Nature Communications

Fig. 2: Detection of sSR-A in a large-scale, multicenter study.

From: Scavenger receptor-A is a biomarker and effector of rheumatoid arthritis: A large-scale multicenter study

Fig. 2

A large-scale, multicenter study was performed to assess the discriminative power of serum sSR-A for RA using quantitative ELISA. The results of the training cohort, validation cohort 1, validation cohort 2, and the pooled three cohorts were shown, respectively. a Beijing cohort: training cohort (RA = 528; SLE = 254; SS = 120; OA = 72; HC = 480; ***all p < 1E−15), b Inner Mongolia cohort: validation cohort 1 (RA = 213; SLE = 144; SS = 144; OA = 119; HC = 120; ***all p < 1E−15), c Hangzhou cohort: validation cohort 2 (RA = 155; SLE = 80; SS = 55; OA = 32; HC = 100. ***p < 1E–15, =2.1799E−04, =5.9038E−05, and <1E−15, respectively, from left to right), d Pooled three cohorts: pooled all three cohorts’ data together (***all p < 1E−15). Red horizontal lines: means; error bars: SEMs. ***p < 0.001 (Kruskal–Wallis test followed by Dunn’s posttest for multiple comparisons). Source data are provided as a Source Data file.

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