Fig. 3: Effect of LAP2α, MAN1, and LMN B1 knock-down on nuclear polarity.
From: Role of the nuclear membrane protein Emerin in front-rear polarity of the nucleus
a Distribution maps of the nucleus, Golgi, EMD and nesprin-1 in cells with LAP2α knock-down. PNesprin-1 = 0.0007, wo-sided Cramer-von Mises test. The magenta outline represents the F-actin border of the averaged cells. b Distribution maps of the nucleus, Golgi, EMD and nesprin-1 in cells with MAN1 knock-down. PEMD = 6.6 × 10−5, PNesprin-1 = 0.011, two-sided Cramer–von Mises test. The magenta outline represents the F-actin border of the averaged cells.c Distribution maps of the nucleus, Golgi, EMD and nesprin-1 in cells with LMN B1 knock-down. PNesprin-1 = 1.96 × 10−7, wo-sided Cramer–von Mises test. The magenta outline represents the F-actin border of the averaged cells. ***P < 0.001, **P < 0.01, *P < 0.05, ns—not significant. For each distribution map an exact number of cells from three independent experiments is stated in the figure. Source data are provided as Source Data file.
