Fig. 4: B1 and B2 receptor expression.
From: The kallikrein–kinin pathway as a mechanism for auto-control of brown adipose tissue activity
a B1 and B2 receptor mRNA expression in iBAT and iWAT of mice exposed to cold or thermoneutrality for 1 week (n = 5 animals except for iBAT Ucp1 30 °C where n = 3 and iWAT 30 °C all genes where n = 4). Ucp1 is shown as a control for the efficiency of thermogenic challenges. b mRNA expression of B1 and B2 receptors during differentiation (D4–8) and in fully differentiated brown adipocytes (D10) (n = 3 independent cell culture experiments for D4 and D8 and n = 4 for D6 and D10 for B1 and B2 genes; n = 3 for D4 and D8 and n = 6 for D6 and n = 5 for D10 for Ucp1 gene). Ucp1 is shown as a positive control for differentiation. Data are presented as means ± s.e.m. (bars). *P < 0.05, **P < 0.01, and ***P < 0.001 versus corresponding controls; one way ANOVA with Tukey’s post hoc test. Source data are provided as a Source data file.
