Fig. 6: G-by-E interaction. | Nature Communications

Fig. 6: G-by-E interaction.

From: A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank

Fig. 6

The figures present the variance explained by depression-PRS under the exposure of different environmental risk factors. The colour shade of each bar represents one condition of environmental factor, a darker shade represents a risk-conferring condition (i.e. had reported childhood trauma and in the most deprived area). The y axes represent the variance explained (R2 in %) by depression-PRS under the given environmental conditions.

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