Table 1 Duration of block for different compounds without or with a single irradiation event.

From: Light-triggered release of conventional local anesthetics from a macromolecular prodrug for on-demand local anesthesia

Compound

Irradiance (W cm−2)

Irradiation duration (min)

Duration of block (min)a

Tetracaine

0

0

28.6 ± 7.1

CM-T

0

0

43.9 ± 11.4

P407-CM-T

0

0

0

P407-CM-T

0.2

2

19.5 ± 4.5

P407-CM-T

0.3

2

36.5 ± 8.9

P407-CM-T

0.3

5

78.1 ± 24

Saline

0.3

2

0

  1. amean ± SD.