Fig. 5: OL maturation impairment in APO-SUS versus APO-UNSUS mPFC. | Nature Communications

Fig. 5: OL maturation impairment in APO-SUS versus APO-UNSUS mPFC.

From: Interneuron hypomyelination is associated with cognitive inflexibility in a rat model of schizophrenia

Fig. 5

a Schematic representation of IL, PL, and BC in rat brain, adapted from the Paxinos and Watson rat brain atlas. b Number of OLIG2+ OL lineage cells/mm2, P90 IL *p = 0.030 and P90 PL **p < 0.0001 in two-tailed independent samples t-test. c Number of OLIG2+NG2+ OL precursor cells/mm2. d Number of OLIG2+GPR17+BCAS1+ early-myelinating OLs/mm2, P21 IL *p = 0.038, P21 PL *p = 0.012, and P90 PL **p = 0.010 in two-tailed independent samples t-test. e Number of OLIG2+CC1+ OLs/mm2, P90 IL *p = 0.015, P90 PL *p = 0.015, and P90 BC *p = 0.017. Cell counts in the IL, PL, and BC of APO-UNSUS rats versus APO-SUS rats (P21 n = 3–8 and P90 n = 5–8 specified in the graphs). Scale bars 20 µm. Source data are provided as a Source data file.

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