Fig. 4: Only intermediate cells from autoantibody-positive and type 1 diabetes donors display an affected ultrastructure of mitochondria and ER. | Nature Communications

Fig. 4: Only intermediate cells from autoantibody-positive and type 1 diabetes donors display an affected ultrastructure of mitochondria and ER.

From: Large-scale electron microscopy database for human type 1 diabetes

Fig. 4

a Intermediate cells from control donors do not display additional morphological alterations (n = 2), while autoantibody-positive (b; n = 3) and type 1 diabetes (c; n = 6) donors do show a cell stress associated affected ultrastructure looking at diminished mitochondrial cristae, dilation of rough ER, and extraction of material. n indicates the number of donors per group with intermediate cells. Scale bars: 1 µm.

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