Fig. 1: Mitochondrial size and rate of double-membraned intramitochondrial vesicle formation increases with age. | Nature Communications

Fig. 1: Mitochondrial size and rate of double-membraned intramitochondrial vesicle formation increases with age.

From: Vesicular transport mediates the uptake of cytoplasmic proteins into mitochondria in Drosophila melanogaster

Fig. 1

a Immunofluorescent staining of mitochondria from D. melanogaster aged 3 days, 2 weeks, 4 weeks, 5 eight weeks. The green channel is ATP5A staining and the red is phalloidin (Phal) staining of F-actin in the muscle. Scale bars: 10 μm. b Relative abundance of mitochondria of different sizes in the muscle tissue of flies of the four age groups. N = 208, 141, 124, and 84 from left to right bars. Statistical test: Chi-Square Test (**p < 0.01; ****p < 0.0001). c TEM images of intramitochondrial vesicles from flies aged 1- and 8-week-old (white arrowhead indicates an intramitochondrial vesicle). d The percentage of vesicle-containing mitochondria in flies aged 1 and 8 weeks (mean ± SD). N = 718 and 265 from left to right bars. Statistical test: Two-tailed Mann–Whitney U-test (***p < 0.001). Source data are provided as a Source Data file.

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