Fig. 2: Cryo-EM 3D reconstruction density map of the Ac-E46K α-syn fibril.

Fibril width, length of half pitch (180° helical turn), helical rise and twist angle are indicated. The twist angle is graphically illustrated. The two intertwining protofilaments are colored in yellow and purple, respectively. Graphing was performed with UCSF Chimera v1.13.