Fig. 2: Tiled-C generates high-resolution contact matrices from small numbers of cells. | Nature Communications

Fig. 2: Tiled-C generates high-resolution contact matrices from small numbers of cells.

From: Dynamics of the 4D genome during in vivo lineage specification and differentiation

Fig. 2

Tiled-C contact matrices of ~3.3 Mb spanning the mouse α-globin locus at 5 kb resolution, generated from small aliquots of primary mature erythroid cells. Contact frequencies represent normalized, unique interactions in three replicates. TADs are indicated below each matrix with a black bar. Gene annotation (α-globin genes highlighted in red), open chromatin (ATAC), and CTCF occupancy are shown below the matrices. Coordinates (mm9): chr11:29,900,000–33,230,000.

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