Fig. 6: Increased IL-15Rβ expression and SRC in older human CD8+ T cells.

a IL-15Rβ MFI directly ex vivo on CD8 T cell subsets from individual young (20–30 yo) or older (60–80 yo) adult human donors (n = 6–7) and b Representative histograms of IL-15Rβ expression, with expression on CD4+ T cells used as a control. c OCR for enriched CD8+ T cells from young or older human donors and d change in OCR for young or older human donors. This experiment was performed once. Bars or datapoints represent mean ± SEM. * Indicates p ≤ 0.05, ** indicates p ≤ 0.01, unpaired t test.