Fig. 3: Binding of biogenic amines and eicosanoids to CxD7L2 by ITC. | Nature Communications

Fig. 3: Binding of biogenic amines and eicosanoids to CxD7L2 by ITC.

From: ADP binding by the Culex quinquefasciatus mosquito D7 salivary protein enhances blood feeding on mammals

Fig. 3

Binding experiments were performed on a VP-ITC microcalorimeter. The upper curve in each panel shows the measured heat for each injection, while the lower graph shows the enthalpies for each injection and the fit to a single-site binding model for calculation of thermodynamic parameters. Titration curves are representative of two measurements. Panels: serotonin (a), histamine (b), epinephrine (c), norepinephrine (d), LTE4 (e), LTC4 (f), LTD4 (g), LTE4 (h), arachidonic acid (i), TXA2 analog U-46619 (j), ATP (k), and ADP (l). The insets show the names and chemical formulas for these compounds.

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