Fig. 4: Methylation clusters differ in mutation landscapes and potential driver genes, and gene set enrichment analysis for H3-Medulla and H3-Pons.
From: The integrated genomic and epigenomic landscape of brainstem glioma
a Frequency of mutations in each gene, grouped by clusters. b Potential driver and significant noncoding mutations for each cluster. c Enriched pathways in H3-Medulla (d) Enrichment Plot from H3-Medulla: KEGG Graft versus host disease (e) Enrichment plot from H3-Medulla Reactome Interferon gamma signaling (f) Enriched pathways in H3-Pons (g) Enrichment plot from H3-Pons: Reactome Processing of capped intron-containing pre-mRNA (h) Enrichment plot from H3-Pons: Reactome DNA replication.
