Fig. 1: MOF-catalyzed selective hydrolysis of glycosyl bonds of sucrose 1.
From: Hydrolase–like catalysis and structural resolution of natural products by a metal–organic framework
a Schematic representation of the one-pot selective hydrolysis/adsorption/crystal resolution of a natural product within a MOF. b 1H NMR spectra of sucrose 1 before and after selective hydrolysis with MOF 2, and SCXRD resolution of fructose fragment 1a. c Evolution with time of naringin 10 in CD3CN after reaction with MOF 2 at 60 °C, followed by 1H NMR. d Hydrolysis and incorporation of the alkyl part of naringin 10 into MOF 2 or MOF 3 with time for different amounts of MOFs (left) and initial rate as a function of the amount of MOF 2 employed (right), according to 1H NMR integrations. Reaction rates were measured with the initial points up to 30% conversion. Lines are a guide to the eye. Error bars account for a 5% uncertainty.
