Fig. 3: Residual lobe measure growth trajectories after accounting for global measures. | Nature Communications

Fig. 3: Residual lobe measure growth trajectories after accounting for global measures.

From: Motion corrected MRI differentiates male and female human brain growth trajectories from mid-gestation

Fig. 3

Graphs of residual lobe measures of volume, surface area, and average absolute mean curvature after covarying for intracranial volume, total brain area, and average brain curvature, respectively. Model fits are shown for male and female data after transformation back to the measurement domain for visualization. The earlier expansion of the frontal lobe is followed by increases in parietal, temporal, and then occipital lobes over the 18 weeks of growth, each contributing to the global measure and resulting in a complex residual growth trajectory. The cortical tissue volume (top row) is seen to follow almost identical trajectories in male and female fetuses in all lobes, occupying the same proportion of ICV at all ages, while residual growth of white matter volume, surface area, and curvature diverge in different lobes.

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