Table 1 Search, visualization, analysis/integration, and download functionalities provided by each of the PCAWG data resources.
From: A user guide for the online exploration and visualization of PCAWG data
Functionality | ICGC Data Portal | UCSC Xena | Chromothripsis Explorer | Expression Atlas | PCAWG-Scout |
---|---|---|---|---|---|
Search | |||||
Search by demographic data, specimen phenotype, molecular subtype | Y | Y | Y | ||
Search by genes and/or variants | Y | Y | Y | Y | |
Search by genomic coordinates | Y | Y | |||
Visualize | |||||
Visualize multiple types of data together | Y | Y | Y | Y | |
Visualize coding variants | Y | Y | Y | Y | |
Visualize non-coding variants | Y | Y | Y | ||
Visualize structural variants | Y | Y | Y | ||
Visualize mutational signatures and predicted drivers | Y | ||||
Visualize genome-wide profiles, including LOH, in Circos plots | Y | ||||
Visualize tissue expression on a human figure | Y | ||||
Visualize gene co-expression | Y | Y | |||
Visualize pathways, therapeutic associations | Y | Y | |||
Visualize summary of BAMs/VCFs | Y | ||||
Analysis | |||||
Kaplan–Meier analysis with statistics | Y | Y | Y | ||
Gene set/pathway enrichment analysis | Y | Y | Y | ||
View non-identifiable analysis results of protected data | Y | Y | Y | Y | |
Discover differentially or co-expressed genes, mutually exclusive genomic events | Y | ||||
Annotations from other resources | Y | Y | Y | Y | |
Download | |||||
Programmatic data download | Y | Y | Y | Y | |
Download BAMs, VCFs, primary files | Y | ||||
Download secondary processed data | Y | Y | Y | Y |