Table 2 Pairwise amino acid sequence identity and similarity of full length or kinase domains of RIPK3 orthologues.

From: Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues

Species

Mouse identity (similarity) %

Human identity (similarity) %

Full length

Kinase domain

Full length

Kinase domain

Mouse

–

–

60.0 (76.1)

70.0 (85.7)

Rat

76.4 (88.0)

82.1 (91.6)

60.4 (76.7)

70.8 (84.3)

Pig

58.6 (77.1)

69.3 (85.3)

62.7 (79.6)

71.2 (85.8)

Horse

60.9 (78.0)

71.7 (87.3)

64.5 (80.1)

74.2 (87.4)

Chicken

–

–

–

–

Tuatara

40.2 (67.5)

42.0 (67.9)

41.2 (65.7)

43.8 (68.0)

Frog

33.8 (59.5)

38.4 (64.9)

33.8 (62.1)

38.2 (64.8)

Stickleback

23.2 (53.6)

n/a

23.2 (53.6)

n/a

  1. Alignments performed with lalign (https://www.ebi.ac.uk/Tools/psa/lalign/)70.