Fig. 3: Comparison of room-temperature and low-temperature structures. | Nature Communications

Fig. 3: Comparison of room-temperature and low-temperature structures.

From: Structural plasticity of SARS-CoV-2 3CL Mpro active site cavity revealed by room temperature X-ray crystallography

Fig. 3

a A superposition of our room temperature ligand-free structure of 3CL Mpro (magenta) with the ligand-free structure of 3CL Mpro (PDB ID 6Y2E) obtained at 100 K (cyan). b Residues 192–198 in the P5 binding pocket differ in conformation between the room temperature and 100 K structures.

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