Table 1 Genetic correlation between migraine and blood pressure.

From: A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine

Method

Trait 1

Trait 2

rg

P*

gcov

gcov_se

LDSC

Any migraine

DBP

0.11

3.56 × 10−06

0.018

0.009

SBP

0.06

0.01

0.004

0.009

PP

−0.01

0.75

−0.009

0.008

Migraine with aura

DBP

0.17

1.50 × 10−03

−0.006

0.008

SBP

0.10

0.04

−0.014

0.008

PP

0.00

0.92

−0.015

0.007

Migraine without aura

DBP

0.14

1.20 × 10−03

0.014

0.008

SBP

0.03

0.43

0.010

0.008

PP

−0.08

0.06

0.002

0.007

GNOVA

Any migraine

DBP

0.12

3.45 × 10−07

0.009

0.002

SBP

0.07

4.64 × 10−03

0.005

0.002

PP

0.00

0.94

0.000

0.002

Migraine with aura

DBP

0.15

1.90 × 10−05

0.008

0.002

SBP

0.10

2.57 × 10−03

0.006

0.002

PP

0.03

0.33

0.002

0.002

Migraine without aura

DBP

0.13

1.86 × 10−04

0.008

0.002

SBP

−0.02

0.66

−0.001

0.002

PP

−0.12

2.12 × 10−04

−0.006

0.002

  1. rg Genetic correlation, gcov genetic covariance, gcov_se standard error of genetic covariance, LDSC LD score regression, GNOVA genetic covariance analyzer, DBP diastolic blood pressure, SBP systolic blood pressure, PP pulse pressure.
  2. *P-value was calculated for the genetic correlation in LDSC and for the genetic covariance in GNOVA, P-values are based on two-sided Wald test.