Fig. 3: In vivo citrullination and glycation analyses.
From: Protein arginine deiminase 4 antagonizes methylglyoxal-induced histone glycation
a Left: western blot analysis of both soluble and histone fractions of wild-type and PAD4-overexpressing 293 T cells. Right: western blot analysis of the histone fraction taken from the same cells that were treated with increasing concentration of MGO. b Western blot analysis of clinical tumor (T) and nontumor (NT) samples from five different breast cancer patients (P1-P5) (left) or breast cancer xenografts (right).
