Fig. 3: Benchmarking of IgCaller: IGLC rearrangements, CSR, and oncogenic Ig translocations. | Nature Communications

Fig. 3: Benchmarking of IgCaller: IGLC rearrangements, CSR, and oncogenic Ig translocations.

From: IgCaller for reconstructing immunoglobulin gene rearrangements and oncogenic translocations from whole-genome sequencing in lymphoid neoplasms

Fig. 3

a Agreement between the IGLC productive rearrangement detected by IgCaller and FC analysis. b TTFT and OS of patients with CLL according to the presence of IGLV3-21 rearrangements. P values for TTFT curves are from Gray test. P values for the multivariate analysis of OS are from Cox regression. c Comparison of the CSR identified by IgCaller and FC. d TTFT of CLL patients according to the presence of CSR. P values are from Gray test. e Circular representation of the oncogenic Ig rearrangements (translocations and deletions) identified by IgCaller genome-wide. Frequencies of recurrent alterations are shown. Source data are provided as a Source data file.

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