Fig. 3: Exhaustion of T cells in SARS-COV-2 infected patients.
From: Immunological and inflammatory profiles in mild and severe cases of COVID-19
a, b PD-1 expression on CD8+ T and CD4+ T cells in HC (n = 6), mild (n = 29), and severe (n = 12) patients of SARS-COV-2 infection. c, d TIM-3 expression on CD8+ T and CD4+ T cells in HC (n = 6), mild (n = 29), and severe (n = 12) patients of SARS-COV-2 infection. Colored symbols indicated deceased cases. Data are expressed as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, by two-tailed Mann–Whitney U-test for b (p = 0.032 and p = 0.0005) and d (p = 0.0076 and p = 0.0105 for Tim-3+CD8+ T cells, and p = 0.0185 and p = 0.0496 for Tim-3+CD4+ T cells, respectively). Source data included as a Source Data File.
