Fig. 3: Structural feature of A4 and NA epitope.

Docked poses of the model epitopes for a wt NA and b I223R/H275Y NA in CDR of A4. Calculated binding modes of the model epitopes for c wt NA and d I223R/H275Y NA in CDR of A4. The β-strands of A4 and carbon atoms of NA epitopes are indicated in cyan and green, respectively. Dotted lines indicate the hydrogen bonds.