Fig. 6: Coherent motion responses of single cells.
From: Distributed and retinotopically asymmetric processing of coherent motion in mouse visual cortex
a Schematic of the two-photon microscopy experimental setup. b Example two-photon imaging field from V1. Each neuron is color-coded by its preferred direction; the opacity of the color corresponds to its mean activity level. Scale bar is 100 µm. c Top: polar plot of coherent motion correlation for each motion direction. Bottom: responses of a single example neuron to each of the eight motion directions, highlighting the direction selectivity of an individual neuron. The coherence trace for this session is overlaid on each neural response. d Responses of each cell in the example session, grouped by preferred direction (left, arrows) and ordered by decreasing coherent motion correlation. e Polar plot of averaged directional tuning to coherent motion across all cells in the example session. f Histogram of 30° binned preferred direction of all neurons across all sessions. Note the significant non-uniformity across all sessions (n = 3461 cells from 13 mice, p = 1.73 × 10−6, Hodges–Ajne test for non-uniformity). g Mean coherent motion correlation across HVAs. Each point represents the mean coherent motion correlation of all the cells in that session. Although all areas exhibit significant coherent motion correlations (V1: p = 1.6 × 10−17; LM: p = 1.3 × 10−5; PM: p = 3.6 × 10−6; AM: p = 2.2 × 10−6), areas AM and PM have significantly higher coherent motion correlations than area V1 (PM: p = 1.3 × 10−2; AM: p = 1.7 × 10−3; two-tailed unpaired two-sample t test). *p < 0.05; **p < 0.01, two-sample t test.
