Fig. 4: Proteins Pop1 and Pop4 stabilize the overall RNase MRP RNA structure and undergo RNA-driven remodeling.
From: Cryo-EM structure of catalytic ribonucleoprotein complex RNase MRP
a Interactions of Pop1 (red), Pop6 (gray), and Pop7 (pale green) with RNase MRP RNA (gray). b, c The fold of the N-terminal part of Pop1 in RNase MRP differs from that in RNase P21. The N-terminal parts of Pop1 are shown in red; the similarly folded C-terminal parts of Pop1 are shown in gray. Interactions of Pop4 (green) with the RNA components of RNase MRP (d) and RNase P21 (e). RNA elements are marked and color coded according to Fig. 1a, b. The part of the Pop4 α3 helix that folds differently in RNase MRP and RNase P is boxed.
