Fig. 1: Ultradistal forearm BMD Genome-wide association analysis results. | Nature Communications

Fig. 1: Ultradistal forearm BMD Genome-wide association analysis results.

From: MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk

Fig. 1

Manhattan (upper panel) and QQ-plot (lower panel) in HUNT dataset (N = 19,705) for ultradistal forearm bone mineral density (BMD) genome-wide association analysis. In the Manhattan plot (upper panel) the genome-wide significance threshold (P-value < 5 × 10−8) is shown using a red dotted line. In the QQ-plot (lower panel), the tested variants have been divided into four groups based on MAF (red dots = MAF [0.05; 0.5], blue dots = MAF [0.005; 0.05], green dots = MAF [0.001; 0.005], purple dots = MAF [0.000253; 0.001]). MAF: minor allele frequency. −log10P: −1 × tenth logarithm of the association test P-value.

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