Table 1 Accuracy of PanSeer.

From: Non-invasive early detection of cancer four years before conventional diagnosis using a blood test

  

Training set

Test set

Category

Total

# of Samples

Specificity (%, 95% CI)

Sensitivity (%, 95% CI)

# of Samples

Specificity (%, 95% CI)

Sensitivity (%, 95% CI)

Healthy

414

207

94.7 (90.7–97.3)

 

207

96.1 (92.5–98.3)

 

Post-diagnosis

223

110

 

88.2 (80.6–93.6)

113

 

87.6 (80.1–93.1)

Pre-diagnosis

191

93

 

91.4 (83.8–96.2)

98

 

94.9 (88.5–98.3)

0–1 year before diagnosis

 

22

 

100 (84.6–100)

21

 

95.2 (76.2–99.9)

1–2 year before diagnosis

 

21

 

90.5 (69.6–98.8)

23

 

95.7 (78.1–99.9)

2–3 year before diagnosis

 

19

 

94.7 (74.0–99.9)

31

 

93.6 (78.6–99.2)

3–4 year before diagnosis

 

31

 

83.9 (66.3–94.6)

23

 

95.7 (78.1–99.9)

  1. Sensitivity and specificity for the training set and test set are presented and divided into subcategories by the number of years prior to cancer diagnosis by conventional testing.