Table 1 Accuracy of PanSeer.
From: Non-invasive early detection of cancer four years before conventional diagnosis using a blood test
Training set | Test set | ||||||
---|---|---|---|---|---|---|---|
Category | Total | # of Samples | Specificity (%, 95% CI) | Sensitivity (%, 95% CI) | # of Samples | Specificity (%, 95% CI) | Sensitivity (%, 95% CI) |
Healthy | 414 | 207 | 94.7 (90.7–97.3) | 207 | 96.1 (92.5–98.3) | ||
Post-diagnosis | 223 | 110 | 88.2 (80.6–93.6) | 113 | 87.6 (80.1–93.1) | ||
Pre-diagnosis | 191 | 93 | 91.4 (83.8–96.2) | 98 | 94.9 (88.5–98.3) | ||
0–1 year before diagnosis | 22 | 100 (84.6–100) | 21 | 95.2 (76.2–99.9) | |||
1–2 year before diagnosis | 21 | 90.5 (69.6–98.8) | 23 | 95.7 (78.1–99.9) | |||
2–3 year before diagnosis | 19 | 94.7 (74.0–99.9) | 31 | 93.6 (78.6–99.2) | |||
3–4 year before diagnosis | 31 | 83.9 (66.3–94.6) | 23 | 95.7 (78.1–99.9) |