Fig. 3: SARS-CoV-2 antibody levels by demographic and clinical variables. | Nature Communications

Fig. 3: SARS-CoV-2 antibody levels by demographic and clinical variables.

From: Seroprevalence of antibodies against SARS-CoV-2 among health care workers in a large Spanish reference hospital

Fig. 3

Levels (median fluorescence intensity, MFI) of IgM, IgG, and IgA against Receptor Binding Domain (RBD) of the SARS-CoV-2 Spike glycoprotein by sex (a), age (b), symptoms (c), and duration of symptoms (d). For (a–c), data are shown only for seropositive subjects for IgM (N = 36), for IgG (N = 44), and for IgA (N = 47). For (d), data are shown only for seropositive and symptomatic subjects for IgM (N = 31), for IgG (N = 40), and for IgA (N = 41). Percentages indicate the proportion of seropositive subjects within each category of the x-axis. The center line of boxes depicts the median of MFIs; the lower and upper hinges correspond to the first and third quartiles; the distance between the first and third quartiles corresponds to the interquartile range (IQR); whiskers extend from the hinge to the highest or lowest value within 1.5 × IQR of the respective hinge. Wilcoxon rank test was used to assess statistically significant differences in antibody levels between groups in (a, c and d). Spearman test was used to calculate the correlation coefficients (r) and p values (p) in (b), where the black line depicts linear regression and the blue curve represents nonlinear regression calculated using the LOESS (locally estimated scatterplot smoothing) method.

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