Fig. 4: SARS-CoV-2 antibody levels by time since onset of symptoms in seropositive subjects.

Levels (median fluorescence intensity, MFI) of IgM, IgG, and IgA against Receptor Binding Domain of the SARS-CoV-2 Spike glycoprotein by days since onset of any symptom. Data are shown only for seropositive subjects with any symptom compatible with COVID-19 (n = 30 for IgM, 39 for IgG, and 40 for IgA). The fitting curve was calculated using the LOESS (locally estimated scatterplot smoothing) method. Shaded areas represent 95% confident intervals. One subject seropositive for the three isotypes and who started symptoms 40 days before serological testing is not shown.