Fig. 1: rs72725854 lies in a prostate cancer-specific enhancer. | Nature Communications

Fig. 1: rs72725854 lies in a prostate cancer-specific enhancer.

From: A rare variant of African ancestry activates 8q24 lncRNA hub by modulating cancer associated enhancer

Fig. 1

a UCSC genome browser snapshot at rs72725854 region and its linked SNP rs114798100 showing ChIP-seq tracks for H3K27Ac, PolII, AR, Med1, and FOXA1. b Graph showing DHS signal around the rs72725854 region in various cell lines. c Genome browser snapshots show ChIP-seq signal of FOXA1 in prostate tumor, LNCaP cells; DHS and H3K27ac in LNCaP and prostate epithelial cells (PrEC). d IGV genome browser snapshot shows ATAC-seq signal around rs72725854 region in seven prostate adenocarcinoma tumor samples with two replicates each from TCGA.

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