Table 4 Association between ZIKV laboratory results, clinical findings, and gestational age at infection.

From: Zika virus vertical transmission in children with confirmed antenatal exposure

  

Any positive ZIKV-Lab result (N = 84)

Any negative ZIKV-Lab result (N = 46)

 
 

All infants

n

%

n

%

p-Value

All infants

130

84

65%

46

35%

 

 Infants with abnormal findingsa 

45

29

64%

16

36%

0.98

 Infants with no abnormal findingsa

85

55

65%

30

35%

 

Brain Imaging

113

74

65%

39

35%

0.37

 Structural abnormalities

14

11

79%

3

21%

 

Fundoscopy

109

68

62%

41

38%

0.41

 Abnormal

6

5

83%

1

17%

 

Hearing Assessment

91

60

66%

31

34%

0.09

 Abnormal

11

10

91%

1

9%

 

Neurologic exam

130

84

65%

46

35%

0.94

 Abnormal

25

16

64%

9

36%

 

Gestational age assessment

130

84

65%

46

35%

0.74

 Small for gestational age

10

6

60%

4

4%

 

Neurodevelopment

129

83

64%

46

36%

0.76

 Abnormal Bayley-III or HINES

17

12

71%

5

29%

 

Gestational Trimester of Infection

130

84

65%

46

35%

 

 First

40

31

78%

9

23%

0.04

 Second

61

39

64%

22

36%

 

 Third

29

14

48%

15

52%

 
  1. Pearson’s chi-square with Yates’ continuity correction was used unless expected cell count was <5, then Fisher’s exact test was used.
  2. aIncludes abnormal hearing, eye, gestational age size assessment, neurodevelopment, neurological exam, or structural brain abnormality.
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