Table 1 Atlas of peptide hormone glycosylation.
From: An atlas of O-linked glycosylation on peptide hormones reveals diverse biological roles
Family name | Peptide hormones | Brain pig | Brain rat | Cerebellum pig | Cerebellum rat | Heart pig | Heart rat | Pancreas pig | Pancreas rat | Ileum pig | Prostate human | CSF human | Plasma human | N2a mouse | STC-1 mouse | Phosphorylateda |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
7B2 | C-terminal peptide | X | – | X | – | – | – | – | – | – | – | – | – | X | – | X |
7B2 | N-terminal peptide | X | X | – | – | – | – | X | – | X | – | X | – | X | X | X |
7B2 | Neuroendocrine protein 7B2 | X | X | X | – | – | – | X | – | X | – | X | – | X | X | X |
ACBP | Acyl-CoA-binding protein | – | – | X | – | – | – | – | – | – | – | – | – | – | – | – |
ADH | Copeptin | – | X | – | – | – | – | – | – | – | – | – | – | – | – | – |
Bombesin | Gastrin-releasing peptide | X | X | – | X | – | – | – | – | X | – | – | – | – | – | – |
Calcitonin | Calcitonin gene-related peptide 1 | – | – | – | X | – | – | – | – | – | – | – | – | – | – | – |
Calcitonin | Calcitonin gene-related peptide 2 | X | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Calcitonin | Islet amyloid polypeptide | – | – | – | – | – | – | – | X | – | – | – | – | – | X | – |
Calcitonin | Katacalcin | – | – | – | – | – | – | – | – | – | X | – | – | – | – | – |
CCKs | Cholecystokinin-25/33/39/58/(desnopeptide) | X | – | X | – | – | – | – | – | X | – | – | – | – | X | – |
CCKs | Gastrin-71 | – | – | – | – | – | – | – | – | X | – | – | – | – | – | – |
Granins | CCB peptide | X | – | X | – | – | – | – | – | – | – | – | – | – | – | X |
Granins | EA-92 | X | X | X | X | X | – | X | – | X | X | X | – | X | X | X |
Granins | ES-43 | X | X | X | X | X | X | X | X | X | X | X | – | X | X | – |
Granins | GAWK peptide | – | – | – | X | – | – | – | – | – | X | X | – | X | X | X |
Granins | GR-44/ER-37 | – | – | – | – | – | – | – | – | – | – | – | – | – | X | – |
Granins | GV-19 | – | – | – | – | – | – | – | – | – | – | – | – | X | – | X |
Granins | Pancreastatin | – | X | – | X | – | – | X | – | X | – | – | – | X | X | – |
Granins | Chromogranin-A | X | X | X | X | X | X | X | X | X | X | X | – | X | X | X |
Granins | Secretogranin-1 | X | X | X | X | X | – | X | X | X | X | X | – | X | X | X |
Granins | Secretogranin-2 | X | X | X | X | – | – | – | – | X | – | – | – | X | X | X |
Granins | Secretogranin-3 | X | X | X | X | X | – | – | – | X | – | X | – | X | X | X |
Granins | Secretoneurin | X | X | – | X | – | – | – | – | – | – | – | – | X | X | X |
Granins | Vasostatin-1 | X | – | X | – | – | – | X | – | X | X | – | – | X | X | X |
Granins | Vasostatin-2 | X | X | X | X | – | – | X | – | X | X | – | – | X | X | X |
Granins | WE-14 | – | – | – | – | – | – | – | – | – | – | – | – | X | – | – |
Cystatin | Kininogen-1 | – | X | – | X | – | X | – | X | X | X | X | X | – | – | – |
Cystatin | Kininogen-1 heavy chain | – | – | – | – | – | – | – | – | X | X | X | X | – | – | – |
Cystatin | Kininogen-1 light chain | – | X | – | X | – | X | – | X | – | X | X | X | – | – | – |
Galanin | Galanin | – | – | – | – | – | – | – | – | – | X | – | – | – | – | – |
Galanin | Galanin message-associated peptide | – | – | – | – | – | – | – | – | X | – | – | – | – | – | X |
Glucagon | Glicentin-related polypeptide | – | – | – | – | – | – | – | – | X | – | – | – | – | – | – |
Glucagon | Glucagon-like peptide 1’s | – | – | – | – | – | – | – | – | X | – | – | – | – | X | – |
Glucagon | Glucagon/glicentin | – | – | – | – | – | – | X | X | X | – | – | – | – | – | – |
Glucagon | Intestinal peptide PHM-27/PHV-42 | X | X | – | – | – | – | – | – | X | X | – | – | – | – | – |
Glucagon | Oxyntomodulin | – | – | – | – | – | – | X | X | X | – | – | – | – | – | – |
Glucagon | Secretin | – | – | – | – | – | – | – | – | – | – | – | – | X | X | – |
Glucagon | Vasoactive intestinal peptide | X | X | X | – | – | – | – | – | X | X | – | – | – | – | – |
GnRH | GnRH-associated peptide 1 | X | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
GnRH | Progonadoliberin-1 | X | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Insulin | Insulin B chain | – | – | – | – | – | – | X | X | – | – | – | – | – | – | – |
Insulin | Insulin-like growth factor II/Ala-25 Del | – | – | – | – | – | – | – | – | – | – | X | – | – | – | – |
Insulin | Preptin | X | – | X | – | X | – | X | – | X | X | X | X | – | – | – |
KISS1 | Metastasis-suppressor KiSS-1 | X | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
KISS1 | Metastin | X | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
MCH | Neuropeptide-glycine-glutamic acid/pro-MCH | – | X | – | X | – | – | – | – | – | – | – | – | – | – | – |
NA | Adiponectin | – | X | – | – | – | – | – | – | – | – | – | – | – | – | – |
NA | Agouti-related protein | X | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Natriuretic peptide | Atrial natriuretic factor | – | – | – | – | X | – | – | – | – | – | – | – | – | – | – |
Natriuretic peptide | Cardiodilatin-related peptide | X | – | – | – | X | X | – | – | – | – | – | – | – | – | – |
Natriuretic peptide | Natriuretic peptides B | X | – | – | – | X | X | – | – | – | – | – | – | X | – | – |
Neurexophilin | Neurexophilin-2 | X | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
NPY | C-flanking peptide of NPY | X | X | – | – | – | X | – | X | – | X | – | – | – | – | X |
NPY | Neuropeptide Y | X | – | – | – | – | – | – | – | – | X | – | – | – | – | X |
NPY | Pancreatic hormone (PPY) | – | – | – | – | – | – | X | X | – | – | – | – | – | – | – |
NPY | Peptide YY/(3–36) | – | – | – | – | – | – | X | – | X | – | – | – | X | – | – |
Nucleobindin | Nesfatin-1 | – | – | – | – | X | – | X | X | X | – | – | – | X | X | – |
Nucleobindin | Nucleobindin-1 | X | X | X | X | X | X | X | X | X | X | X | X | X | X | – |
Nucleobindin | Nucleobindin-2 | X | X | X | X | X | X | X | X | X | X | – | – | X | X | – |
Opioid | Neuropeptide 1 | X | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Parathyroid hormone | PTHrP/PTHrP[38–94] | X | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
POMC | Beta-endorphin/lipotropin beta/NPP | X | X | – | X | – | – | – | – | – | – | – | – | – | – | – |
ProSAAS | Big LEN/little LEN/big PEN-LEN | – | X | – | X | – | – | – | X | – | – | X | – | X | X | X |
ProSAAS | Big SAAS/little SAAS | X | – | X | – | – | – | – | – | – | – | – | – | X | X | X |
ProSAAS | proSAAS | X | X | X | X | – | – | – | X | – | – | X | – | X | X | X |
Serpin | Angiotensinogen | – | – | – | – | – | – | – | – | – | X | – | – | – | – | – |
Somastostatin | Somatostatin-28 | – | – | – | – | – | – | – | – | X | – | – | – | – | – | X |
Tachykinin | C-terminal-flanking peptide | X | – | – | – | – | – | – | – | – | – | – | – | – | X | – |
TRH | Pro-thyrotropin-releasing hormone | X | – | – | – | – | – | – | – | X | – | – | – | – | – | – |
VGF | Antimicrobial peptide VGF[554–577] | – | X | – | – | – | – | – | – | – | – | – | – | – | – | – |
VGF | Neurosecretory protein VGF | X | X | X | X | – | – | – | – | – | X | X | – | – | – | – |
