Fig. 6: Compositional changes of myeloid cells and their interactions with other cells. | Nature Communications

Fig. 6: Compositional changes of myeloid cells and their interactions with other cells.

From: Single-cell transcriptomic analysis in a mouse model deciphers cell transition states in the multistep development of esophageal cancer

Fig. 6

a tSNE plots of 6177 myeloid cells, colored by cluster. b Histogram showing myeloid cells composition across the six pathological stages. Color indicates cluster designated in a. c Line chart displaying changing trend of the five selected cluster proportions across the six pathological stages. d Heatmap showing scale normalized expression of the immune co-stimulation (left panel) or suppression (right panel) genes in the 11 clusters of myeloid cells. e Heatmap showing scale normalized expression of selected Ccl and Cxcl chemokines, and their corresponding receptors in representative clusters of epithelial cells, fibroblasts, myeloid cells, and T cells. f Bubble plot showing scale normalized expression of the selected genes along tumorigenesis process in various cell types. Size of dots represents percentage of cells expressing corresponding genes across pathological stages.

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