Fig. 3: Transcriptional analysis of the FliA_R94K mutant that led to improved C3–C4 alcohol tolerance.
From: Engineering regulatory networks for complex phenotypes in E. coli

a Pie chart showing categories of genes that were up-/downregulated more than twofold in the FliA_R94K mutant compared with the nontargeting control. The numbers from the pie chart are gene numbers and the percentage of each category for genes with significant transcriptional changes. b The number of transcripts for the fliA gene in the FliA_R94K mutant and nontargeting control under different conditions. c–e Number of genes with significant transcriptional changes for different biological processes: c protein and membrane metabolic process, d energy metabolic process, and e response to stimulus.