Fig. 1: MDDEF structure.
From: Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase
The crystal structure of MDDEF in complex with MVAPP, ADPBeF3, and Mg2+ (MDDEF-MVAPP-ADPBeF3-Mg2+) was analyzed by PROMOTIF61. Secondary structure elements, α-helices (red cylinders), 310-helices (gray cylinders) and β-sheets (blue arrows) are drawn and labeled as α, η, and β. The β10-α4 loop and the phosphate-binding loop are shown in cyan. The range of amino acid numbers of each secondary structural element is listed as following: β1(1–15), β2(20–22), β3(27–28), β4(32–49), β5(56–59), β6(62–63), β7(89–96), β8(149–153), β9(162–165), β10(175–180), β11(277–280), β12(287–292), β13(312–315), β14(322–324), α1(66–81), α2(105–120), α3(127–137), α4(191–201), α5(205–224), α6(228–246), α7(258–272), α8(298–303), η1(139–142), η2(171–174), η3(293–297), η4(308–311).
