Fig. 4: Clearance of HIV-1 infections in Hu-HSC mice by SECH.
From: Clearance of HIV infection by selective elimination of host cells capable of producing HIV
a HIV-1 viral RNA levels in the blood of SECH- or ART-treated Hu-HSC mice before and after 2 months of withdrawal of the treatments (ART, n = 5; SECH, n = 15). The dash line indicates detection limit. b Measuring infectious HIV-1 from spleen and bone marrow (BM) cells of HIV-1-infected Hu-HSC mice by TZA. Data are presented as mean ± SD (ART, n = 5 mice; SECH, n = 15 mice). Data are presented as mean ± SD. Each biological sample was measured in three technical replicates. ND, not detectable. c Virus outgrowth assay after adoptive transfer of spleen and BM cells from mice as in c into uninfected Hu-HSC recipient mice. (ART, n = 3 mice; SECH, n = 15 mice). Source data are provided as a Source Data file.
