Fig. 2: Structure of the V1 domain showing three AB heterodimers with distinct conformations.
From: Cryo-EM structures of intact V-ATPase from bovine brain
a Overall structure showing the V1 domain. b The cytosolic view of the V1 domain in state 1 (left) and state 2 (right). c, d The structural comparison of ABopen, ABclosed, and ABsemi in state 1. The domains of the AB heterodimer have been indicated in the left side of panel c. Cryo-EM maps in state 1 are shown at the 4σ level.
